Bone Abstracts

Aim: To assess long term safety of low dose pamidronate therapy and the effects on pubertal growth spurt.Methods: A retrospective study was conducted in 36 girls and 21 boys whose mean age was 4.1±3.6 years at baseline. Intravenous pamidronate 3–4 mg/kg per year once daily therapy with 2–4 cycles/year for 0.5–15 years) was given with physical therapy and orthopedic surgery as appropriate. Mobility score, height, puberty and bone miner...